Argollo A, Reis V L, Niemeyer P, Vuono E
Trans R Soc Trop Med Hyg. 1978;72(1):37-9. doi: 10.1016/0035-9203(78)90296-1.
The authors present a patient with South American blastomycosis with cerebral involvement in whom a ventriculography and a cerebral arteriography showed a tumour at the level of the fourth ventricle. After six months of therapy, clinical cure of some lesions was obtained while the neurological picture of right hemiparesia remained unchanged. Surgery was performed and the histopathological study revealed a tuberculoid, granuloma-forming gumma. The literature is reviewed and comments are made on the cerebro-spinal fluid changes and the types of involvement of the nervous system. The neurological examination and the analysis of the cerebro-spinal fluid indicated that the relative frequency of central nervous system localization in South American blastomycosis was not in agreement with current thought.
作者报告了一例患有南美芽生菌病且累及脑部的患者，该患者的脑室造影和脑动脉造影显示在第四脑室水平有一个肿瘤。经过六个月的治疗，部分病变获得临床治愈，但右半身轻瘫的神经症状仍未改变。随后进行了手术，组织病理学研究显示为结核样、形成肉芽肿的梅毒瘤。本文回顾了相关文献，并对脑脊液变化和神经系统受累类型进行了评论。神经检查和脑脊液分析表明，南美芽生菌病中枢神经系统定位的相对频率与当前观点不一致。
