Somayajulu R S, Mukherjee S P, Lynn W S, Bennett P B
Undersea Biomed Res. 1978 Mar;5(1):1-8.
Chickens exposed to hyperbaric oxygen (3 to 5 ATA) or to 100% oxygen at atmospheric pressure for prolonged periods showed no pathologic pulmonary damage, although hydrogen peroxide did accumulate in their airways. Superoxide dismutase in the peripheral nucleated red blood cells and the rate of oxidation of specifically labeled glucose were increased in chickens exposed to hyperbaric oxygen for three hours. Superoxide dismutase increased in the lung lavage of the rabbits and in the peripheral nucleated red blood cells. Glucose oxidation was unchanged. The difference in superoxide dismutase is probably the result of the desquamated, damaged cells found in the rabbit lung lavage. That only rabbit bronchi are lined with oxidant-sensitive ciliated cells suggests that the absence of these ciliated cells in fowl may well be responsible for the observed resistance of these birds to oxidant damage by oxygen.
长时间暴露于高压氧（3至5个绝对大气压）或常压下的100%氧气中的鸡，尽管气道中确实积累了过氧化氢，但并未显示出病理性肺损伤。暴露于高压氧三小时的鸡，其外周有核红细胞中的超氧化物歧化酶以及特定标记葡萄糖的氧化速率有所增加。兔子肺灌洗物和外周有核红细胞中的超氧化物歧化酶增加。葡萄糖氧化未发生变化。超氧化物歧化酶的差异可能是兔子肺灌洗物中发现的脱落受损细胞所致。仅兔支气管内衬有对氧化剂敏感的纤毛细胞，这表明禽类中缺乏这些纤毛细胞很可能是这些鸟类对氧气氧化损伤具有抵抗力的原因。
