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[弥漫性间质性肺炎。胺碘酮可能的责任。关于一例病例及文献综述]

[Diffuse interstitial pneumonitis. Possible responsibility of amiodarone. Apropos of a case and review of the literature].

作者信息

Ruesch C, Chabry E, Joux A, Bayon M, Emonot A

出版信息

Poumon Coeur. 1983;39(5):263-7.

PMID:6361718
Abstract

We report the case of a 65 years old woman treated for 20 months with Amiodarone for angina who presented a picture of diffuse interstitial pneumonitis of rapid onset and of marked severity, which totally resolved once the drug was suspended and following the administration of steroid therapy. This raises the problem of the responsibility of Amiodarone in the aetiology of diffuse interstitial pneumonitis. We present 12 cases from the literature which also raise the question of the responsibility of this drug.

摘要

我们报告了一例65岁女性患者,因心绞痛接受胺碘酮治疗20个月,出现了快速起病且严重程度显著的弥漫性间质性肺炎。在停用该药物并给予类固醇治疗后,病情完全缓解。这引发了胺碘酮在弥漫性间质性肺炎病因学中责任的问题。我们展示了文献中的12个病例,这些病例也提出了该药物责任的问题。

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