Whisnant J P
Stroke. 1984 Jan-Feb;15(1):160-8. doi: 10.1161/01.str.15.1.160.
Stroke mortality in the United States has declined since 1900. The mortality rates from stroke in Rochester, Minnesota, have declined 76% since 1950, and the primary cause for the declines is a decrease in the incidence of new cases of cerebral infarction and cerebral hemorrhage. There are no data on the incidence of stroke prior to 1945 to confirm the US mortality trend. The decline in incidence was noted in women 10-15 years before it was seen in men. Hypertension is the most important risk factor for stroke. Hypertension surveys have shown an increasing effectiveness of antihypertensive medication in lowering blood pressure, and the effect was noted earlier in women. Available evidence is consistent with the idea that treatment of hypertension is the only significant contributor to the decline of stroke.
自1900年以来，美国的中风死亡率有所下降。自1950年以来，明尼苏达州罗切斯特市的中风死亡率下降了76%，下降的主要原因是脑梗死和脑出血新发病例的发病率降低。1945年以前没有关于中风发病率的数据来证实美国的死亡率趋势。女性发病率的下降比男性早10 - 15年。高血压是中风最重要的危险因素。高血压调查显示，抗高血压药物在降低血压方面的效果越来越显著，而且女性更早出现这种效果。现有证据与以下观点一致，即高血压治疗是中风死亡率下降的唯一重要因素。
