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短光照周期可抵消卵巢切除对田鼠能量平衡的影响。

Short photoperiods counteract the effects of ovariectomy on energy balance of voles.

作者信息

Dark J, Zucker I, Wade G N

出版信息

Am J Physiol. 1984 Jan;246(1 Pt 2):R31-4. doi: 10.1152/ajpregu.1984.246.1.R31.

DOI:10.1152/ajpregu.1984.246.1.R31
PMID:6364838
Abstract

Adult female meadow voles maintained from birth in a long photoperiod (14 h light, 10 h darkness; LD 14:10) were ovariectomized or sham-ovariectomized and housed subsequently in long or short (LD 10:14) photoperiods for 10 wk. Absolute and relative daily food intake, body mass, carcass lipid and water content, and lipoprotein lipase activity of white adipose tissue were reduced in voles housed in short photoperiods. Ovariectomy resulted in increases in food intake and body weight and altered carcass composition in long-day voles, but these changes were negated in voles kept in short photoperiods. Responsiveness to short photoperiods promotes winter weight loss and subsequent energy intake savings and counteracts the body weight increases normally associated with gonadal quiescence and diminished hormone secretion.

摘要

从出生起就饲养在长光照周期(14小时光照,10小时黑暗;LD 14:10)下的成年雌性草甸田鼠接受了卵巢切除或假卵巢切除手术,随后分别饲养在长光照周期或短光照周期(LD 10:14)下10周。饲养在短光照周期下的田鼠,其每日绝对和相对食物摄入量、体重、胴体脂质和水分含量以及白色脂肪组织中的脂蛋白脂肪酶活性均降低。卵巢切除导致长日照田鼠食物摄入量和体重增加,胴体组成改变,但在短光照周期下饲养的田鼠中,这些变化被抵消。对短光照周期的反应促进了冬季体重减轻和随后的能量摄入节省,并抵消了通常与性腺静止和激素分泌减少相关的体重增加。

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