叠瓦癣易感性的常染色体隐性遗传。

Autosomal recessive inheritance of susceptibility to tinea imbricata.

作者信息

Serjeantson S, Lawrence G

出版信息

Lancet. 1977 Jan 1;1(8001):13-5. doi: 10.1016/s0140-6736(77)91653-1.

Abstract

Familial distribution of chronic tinea imbricata in an untreated Melanesian population was consistent with a genetic predisposition to this disease. The pattern suggested that susceptibility to chronic Trichophyton concentricum infection is recessively inherited and controlled by genes at a single autosomal locus. In married couples there was no concordance of the disease above that expected by chance and the observed segregation of tinea imbricata accorded well with that predicted by the genetic hypothesis.

摘要

在一个未经治疗的美拉尼西亚人群中，慢性叠瓦癣的家族分布情况与该疾病的遗传易感性相符。这种模式表明，对同心毛癣菌慢性感染的易感性是隐性遗传的，由一个常染色体位点上的基因控制。在已婚夫妇中，该疾病的一致性并不高于偶然预期的情况，并且观察到的叠瓦癣分离情况与遗传假设所预测的情况非常吻合。