婴儿猝死综合征（SIDS）、非SIDS婴儿及成人肺组织中前列环素（前列腺素I2）的生成
Prostacyclin (prostaglandin I2) formation in lung tissues of infants in sudden infant death syndrome (SIDS), non-SIDS and adults.
作者信息
Seto D S, Matsuo M, Hokama J L, Shirai L K, Hokama Y
出版信息
J Med. 1983;14(5-6):451-9.
SIDS lung tissues elaborated significantly (p less than 0.01) lower PGI2 as compared with non-SIDS and adults. Significant differences (p less than 0.01) between SIDS and non-SIDS were especially shown at 2-4 months of age, 16.46 +/- 6.86 vs. 28.39 +/- 8.86 ng PGI2/50 mg of lung tissue, respectively, for SIDS and non-SIDS. A highly significant difference (p less than 0.001) was shown for SIDS (16.46 +/- 6.86 ng PGI2/50 mg lung tissue) when compared to adults (33.50 +/- 5.60 ng PGI2/50 mg lung tissue). It is suggested that there is defective maturation in the development of prostacyclin synthetase in lung tissues of SIDS infants.
与非婴儿猝死综合征（SIDS）组和成人组相比，SIDS组肺组织中前列环素（PGI2）水平显著降低（p<0.01）。SIDS组与非SIDS组之间的显著差异（p<0.01）尤其在2至4个月龄时表现出来，SIDS组和非SIDS组肺组织中PGI2水平分别为16.46±6.86 ng/50 mg和28.39±8.86 ng/50 mg。与成人组（33.50±5.60 ng/50 mg肺组织）相比，SIDS组（16.46±6.86 ng/50 mg肺组织）有极显著差异（p<0.001）。提示SIDS婴儿肺组织中前列环素合成酶的发育存在成熟缺陷。
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