Samuel N M, Loudon J, Kohsaka K
Lepr India. 1983 Oct;55(4):648-53.
Athymic nude mice were introduced in our laboratories in 1982. In this paper results over one year period of nude mice inoculated with small numbers of M. leprae are described. In this study we showed that 1 X 10(4) M. leprae with low numbers of viable bacilli inoculated into hind foot pads of nude mice housed both in vinyl plastic isolators and "clean room" conditions had the ability to grow and reach remarkable levels. There was dissemination of the infection to other uninoculated foot pads by six months.
无胸腺裸鼠于1982年引入我们的实验室。本文描述了接种少量麻风杆菌的裸鼠一年期间的结果。在本研究中，我们发现，将含有少量活菌的1×10⁴ 株麻风杆菌接种到饲养在乙烯塑料隔离器和“洁净室”条件下的裸鼠后足垫中，该菌具有生长并达到显著数量水平的能力。到6个月时，感染扩散到了其他未接种的足垫。
