Sieck U V, Ohlsson A
Obstet Gynecol. 1984 Mar;63(3 Suppl):22S-24S.
The case of a woman with recurrent hydramnios in three pregnancies, from which the only surviving infant was later found to have Bartter's syndrome, is described. Analysis of electrolytes, renin activity, and aldosterone levels in amniotic fluid from this pregnancy are presented. The finding of maternal hydramnios in the present and 12 other reported cases of Bartter's syndrome suggests that increased fetal voiding is the most likely causative factor in the development of increased amniotic fluid volume. Early onset hydramnios might signify Bartter's syndrome in the offspring in families with an index case. In cases of hydramnios of unknown etiology, appropriate investigations might lead to early diagnosis and treatment of Bartter's syndrome.
本文描述了一名女性在三次怀孕中均出现羊水过多的病例，其唯一存活的婴儿后来被诊断为巴特综合征。文中还呈现了此次怀孕时羊水的电解质、肾素活性及醛固酮水平分析。在本病例及其他12例已报道的巴特综合征病例中均发现母体羊水过多，这表明胎儿排尿增加很可能是羊水量增多的致病因素。对于有索引病例的家庭，早期出现的羊水过多可能预示着后代患有巴特综合征。在病因不明的羊水过多病例中，进行适当检查可能会实现巴特综合征的早期诊断和治疗。
