Harvey J S, Watkins G M, Sherman R T
South Med J. 1984 Feb;77(2):204-14. doi: 10.1097/00007611-198402000-00019.
The estimated 32,600,000 fires that occur annually in the United States produce over 300,000 injuries and 7,500 deaths. Ten percent of hospitalized burn victims die as a direct result of the burn. Initial evaluation and management of the burn patient are critical. The history should include the burn source, time of injury, burn environment, and combustible products. The burn size is best estimated by the Lund and Browder chart, and the burn depth is determined by clinical criteria. Pulmonary involvement and circumferential thoracic or extremity burns require detection and aggressive treatment to maintain organ viability. Hospitalization is usually necessary for adults with burns larger than 10% of the total body surface area (TBSA) or children with burns larger than 5% of TBSA. Major burns, those of 25% or more of TBSA or of 10% or more of full thickness, should be considered for treatment at a burn center, as well as children or elderly victims with burns of greater than 10% TBSA. Lactated Ringer's solution, infused at 4 ml/kg/% TBSA, is generally advocated for initial fluid restoration. After the acute phase (48 hours), replacement of evaporative and hypermetabolic fluid loss is necessary. These losses may constitute 3 to 5 liters per day for a 40% to 70% TBSA burn. Blood transfusion is often required because of persistent loss of red blood cells (8% per day for about ten days). Many electrolyte abnormalities may occur in the first two weeks. Pulmonary injury commonly is lethal. Circumoral burns, oropharyngeal burns, and carbonaceous sputum are indicative of inhalation injury, but arterial blood gas determinations, fiberoptic bronchoscopy, and xenon lung scans are useful for confirming the diagnosis. Humidified oxygen, intubation, positive-pressure ventilation, and pulmonary toilet are the mainstays of therapy for inhalation injury. Wound care is initially directed at preservation of vital function by escharotomy, if restrictive eschar impairs ventilatory or circulatory function. Antibacterial agents may be applied to the burn, but invasive sepsis, defined as greater than 10(5) organisms per gram of tissue with invasion of subjacent viable tissue, requires systemic antibiotic therapy. Wound debridement is done by daily hydrotherapy, tangential excision, chemicals, primary excision, and grafting, tailoring the technique to the individual burn.(ABSTRACT TRUNCATED AT 400 WORDS)
美国每年估计发生3260万起火灾,造成30多万人受伤,7500人死亡。10%的住院烧伤患者直接死于烧伤。烧伤患者的初始评估和处理至关重要。病史应包括烧伤源、受伤时间、烧伤环境和可燃产品。烧伤面积最好用伦德和布劳德图表估算,烧伤深度根据临床标准确定。肺部受累以及胸部或四肢环形烧伤需要及时发现并积极治疗以维持器官的存活能力。成人烧伤面积超过全身表面积(TBSA)的10%或儿童烧伤面积超过TBSA的5%通常需要住院治疗。大面积烧伤,即TBSA的25%或更多或全层烧伤的10%或更多,以及TBSA烧伤超过10%的儿童或老年受害者,应考虑在烧伤中心接受治疗。一般主张以每千克体重每%TBSA输注4毫升乳酸林格氏液进行初始液体复苏。急性期(48小时)过后,需要补充蒸发和高代谢引起的液体丢失。对于TBSA烧伤40%至70%的患者,这些丢失量可能每天达3至5升。由于红细胞持续丢失(约十天内每天8%),常常需要输血。头两周可能会出现许多电解质异常。肺部损伤通常是致命的。口周烧伤、口咽烧伤和含碳痰液提示吸入性损伤,但动脉血气测定、纤维支气管镜检查和氙肺扫描有助于确诊。湿化氧气、插管、正压通气和肺部灌洗是吸入性损伤治疗的主要方法。如果焦痂限制影响通气或循环功能,伤口护理最初旨在通过焦痂切开术来维持重要功能。抗菌剂可应用于烧伤处,但侵袭性脓毒症,定义为每克组织中有超过10(5)个微生物并侵入下方存活组织,需要全身使用抗生素治疗。伤口清创通过每日水疗、削痂、化学方法、一期切除和植皮来进行,根据个体烧伤情况调整技术。(摘要截选至400字)