Bauman W A, Merkle L N, Rachman R A, Mitsuto S M
Diabetes Care. 1984 Jan-Feb;7(1):88-91. doi: 10.2337/diacare.7.1.88.
A 26-yr-old registered nurse who is employed as a diabetes nurse care coordinator had episodes of symptomatic fasting hypoglycemia associated with hyperinsulinemia and a relatively suppressed plasma C-peptide concentration, arousing the suspicion of self-induced illness. However, using a species-specific radioimmunoassay, the species of insulin during an episode of hypoglycemia was determined to be human in origin. Once the patient's illness was attributed to endogenous insulin hypersecretion, prompt surgical intervention and the diagnosis of nesidioblastosis in an adult was made.
一名26岁的注册护士,担任糖尿病护理协调员,出现了与高胰岛素血症相关的症状性空腹低血糖发作,且血浆C肽浓度相对受抑制,这引发了对自身诱导疾病的怀疑。然而,使用种属特异性放射免疫测定法,确定低血糖发作期间胰岛素的种类为人类来源。一旦将患者的病情归因于内源性胰岛素分泌过多,便迅速进行了手术干预,并诊断出一名成年人患有胰岛细胞增殖症。