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关于所谓的 Lennert 淋巴瘤(淋巴上皮样细胞淋巴瘤)疾病实体的一则注释。

A note on the so-called Lennert's lymphoma (lympho epithelioid cellular lymphoma) concerning its disease entity.

作者信息

Tanaka T, Ohnoshi T, Kobayashi K, Hayashi K

出版信息

Acta Pathol Jpn. 1978 Jan;28(1):157-64. doi: 10.1111/j.1440-1827.1978.tb01256.x.

Abstract

Two cases of so-called Lennert's lymphoma, which is characterized by massive infiltrations of focally aggregated epithelioid cells, are presented. Since this lesion was particularly emphasized by LENNERT and MESTDAGH in 1968, the major conflicting issue has been focussed on its precise disease entity whether this is an independent or already-established lymphoproliferative disorder. Based on our experiences, we are rather inclined to regard this lesion to be "a curious histologic variant of an already-established disease entity". In order to investigate its precise disease entity and also in view of a possible significance of the presence of epithelioid histiocytes in the lymph nodes and of tonsillar involvement in relation to immunocompetence of the patients, further accumulation of similar cases is required.

摘要

本文报告了两例所谓的 Lennert 淋巴瘤,其特征为局灶性聚集的上皮样细胞大量浸润。自 1968 年 LENNERT 和 MESTDAGH 特别强调了这种病变以来,主要的争议问题集中在其确切的疾病实体,即这是一种独立的还是已确立的淋巴增殖性疾病。根据我们的经验,我们更倾向于认为这种病变是“一种已确立疾病实体的奇特组织学变体”。为了研究其确切的疾病实体,同时考虑到淋巴结中上皮样组织细胞的存在以及扁桃体受累与患者免疫能力的可能意义,需要进一步积累类似病例。

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