Travers A A
Nucleic Acids Res. 1984 Mar 26;12(6):2605-18. doi: 10.1093/nar/12.6.2605.
E. coli promoters which are coordinately regulated in response to amino acid limitation contain conserved nucleotide sequences immediately 3' to -10 region. These sequences contain predominantly either GC or AT residues depending on whether the response is respectively negative or positive. Certain classes of promoters also contain conserved sequences upstream of the primary promoter. In tRNA genes these sequences could act as a secondary polymerase binding site.
在应对氨基酸限制时受到协同调控的大肠杆菌启动子,在 -10 区域紧邻的 3' 端含有保守核苷酸序列。根据反应分别是阴性还是阳性,这些序列主要含有 GC 或 AT 残基。某些类型的启动子在主要启动子上游也含有保守序列。在 tRNA 基因中,这些序列可作为二级聚合酶结合位点。