[Comparative characteristics of normal and artifactual hyperchromic brain neurons].

Bernhard's method has been used for revealing condensed chromatin and ribonucleoproteid (RNP)-particles. Two types of hyperchromic neurons are described. For hyperchromic neurons present in the normal cerebral tissue, specific signs are: an essential chromatin condensation as dense clumps of various size, normal or slightly increased amount of perichromatin granules (RCG), complete absence of fibrillar RNP, presence in all nuclear areas of interchromatin granules (ICG). In cytoplasm all polysomes are dissociated into separate ribosomes. For artificial hyperchromic neurons specific signs are: chromatin condensation as irregular loose clumps interchanged with karyoplasm striae, a sharp increase of PCG at a decreased amount of fibrillar RNP-particles and a normal size of separate aggregations of ICG, as well as a considerable vacuolization of cytoplasm and an essential pericellular edema.