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酪蛋白吗啡有功能作用吗?

Does casomorphin have a functional role?

作者信息

Petrilli P, Picone D, Caporale C, Addeo F, Auricchio S, Marino G

出版信息

FEBS Lett. 1984 Apr 9;169(1):53-6. doi: 10.1016/0014-5793(84)80288-4.

DOI:10.1016/0014-5793(84)80288-4
PMID:6370722
Abstract

Degradation of buffalo beta-casein by various physiological enzymes was studied. Digestion with gastric and pancreatic proteases plus leucine aminopeptidase did not release casomorphins but a putative precursor (procasomorphin) which was further digested by brush border peptidases into peptides differing from casomorphins.

摘要

研究了各种生理酶对水牛β-酪蛋白的降解作用。用胃蛋白酶、胰蛋白酶和亮氨酸氨肽酶进行消化并未释放出酪蛋白吗啡,但释放出一种假定的前体(前酪蛋白吗啡),该前体被刷状缘肽酶进一步消化成与酪蛋白吗啡不同的肽。

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Does casomorphin have a functional role?酪蛋白吗啡有功能作用吗?
FEBS Lett. 1984 Apr 9;169(1):53-6. doi: 10.1016/0014-5793(84)80288-4.
2
Digestion by pancreatic juice of a beta-casomorphin-containing fragment of buffalo beta-casein.水牛β-酪蛋白含β-酪蛋白吗啡样肽片段的胰液消化作用。
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[Physiological importance of microvilli-bound leucine arylamidase in the final digestion of proteins. 2. Comparison of the exopeptidase activities of purified leucine arylamidase, purified microvilli, and microvilli sediment].
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[Physiological importance of the microvilli-bound leucine arylamidase in the final digestion of proteins. III. Exopeptidatic activities of purified microvilli against peptides mixtures in the presence and after the removal of free amino acids].[微绒毛结合的亮氨酸芳基酰胺酶在蛋白质最终消化中的生理重要性。III. 纯化微绒毛在存在游离氨基酸和去除游离氨基酸后对肽混合物的外肽酶活性]
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In vivo endogenous proteolysis yielding beta-casein derived bioactive beta-casomorphin peptides in human breast milk for infant nutrition.人乳中内源性蛋白水解生成的β-酪蛋白衍生生物活性β-酪啡肽用于婴儿营养。
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Milk from cows of different β-casein genotypes as a source of β-casomorphin-7.不同β-酪蛋白基因型奶牛的牛奶作为β-酪啡肽-7的来源。
Int J Food Sci Nutr. 2012 Jun;63(4):426-30. doi: 10.3109/09637486.2011.634785. Epub 2011 Nov 14.

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Do gluten peptides stimulate weight gain in humans?谷蛋白肽会刺激人体体重增加吗?
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Caseins of various origins and biologically active casein peptides and oligosaccharides: structural and physiological aspects.不同来源的酪蛋白以及生物活性酪蛋白肽和低聚糖:结构与生理学方面
Mol Cell Biochem. 1989 May 4;87(1):5-30. doi: 10.1007/BF00421079.