晚期卵巢癌的化疗
Chemotherapy in advanced ovarian cancer.
作者信息
Rodenburg C J, Cleton F J
出版信息
J Cancer Res Clin Oncol. 1984;107(2):99-105. doi: 10.1007/BF00399380.
Abstract
The chemotherapy of advanced ovarian cancer is reviewed. Treatment with single agents results in low remission rates and few complete remissions. The results have been improved with modern combination chemotherapy, which includes cisplatin, although a longer follow up is needed for definite conclusions to be made concerning survival. Toxicity and drug resistance remain important problems. The future prospects of treatment with emphasis on intraperitoneal chemotherapy are discussed.
摘要
本文综述了晚期卵巢癌的化疗情况。单药治疗缓解率低，完全缓解的病例很少。现代联合化疗（包括顺铂）改善了治疗效果，不过要得出关于生存的确切结论还需要更长时间的随访。毒性和耐药性仍然是重要问题。文中还讨论了以腹腔内化疗为重点的治疗前景。
相似文献
1
Chemotherapy in advanced ovarian cancer.晚期卵巢癌的化疗
J Cancer Res Clin Oncol. 1984;107(2):99-105. doi: 10.1007/BF00399380.
2
A systematic overview of chemotherapy effects in ovarian cancer.卵巢癌化疗效果的系统综述。
Acta Oncol. 2001;40(2-3):340-60. doi: 10.1080/02841860151116420.
3
A rapid and systematic review of the clinical effectiveness and cost-effectiveness of paclitaxel, docetaxel, gemcitabine and vinorelbine in non-small-cell lung cancer.对紫杉醇、多西他赛、吉西他滨和长春瑞滨在非小细胞肺癌中的临床疗效和成本效益进行的快速系统评价。
Health Technol Assess. 2001;5(32):1-195. doi: 10.3310/hta5320.
4
A systematic overview of chemotherapy effects in colorectal cancer.结直肠癌化疗效果的系统综述。
Acta Oncol. 2001;40(2-3):282-308. doi: 10.1080/02841860151116367.
5
A rapid and systematic review of the clinical effectiveness and cost-effectiveness of topotecan for ovarian cancer.拓扑替康治疗卵巢癌的临床有效性和成本效益的快速系统评价。
Health Technol Assess. 2001;5(28):1-110. doi: 10.3310/hta5280.
6
A systematic overview of chemotherapy effects in B-cell chronic lymphocytic leukaemia.B 细胞慢性淋巴细胞白血病化疗效果的系统综述。
Acta Oncol. 2001;40(2-3):224-30. doi: 10.1080/02841860151116303.
7
Adjuvant (post-surgery) chemotherapy for early stage epithelial ovarian cancer.早期上皮性卵巢癌的辅助（术后）化疗。
Cochrane Database Syst Rev. 2012 Mar 14;3(3):CD004706. doi: 10.1002/14651858.CD004706.pub4.
8
Adjuvant (post-surgery) chemotherapy for early stage epithelial ovarian cancer.早期上皮性卵巢癌的辅助（术后）化疗。
Cochrane Database Syst Rev. 2009 Jan 21(1):CD004706. doi: 10.1002/14651858.CD004706.pub2.
9
Topotecan, pegylated liposomal doxorubicin hydrochloride and paclitaxel for second-line or subsequent treatment of advanced ovarian cancer: a systematic review and economic evaluation.拓扑替康、聚乙二醇化脂质体盐酸多柔比星和紫杉醇用于晚期卵巢癌二线或后续治疗：一项系统评价和经济学评估
Health Technol Assess. 2006 Mar;10(9):1-132. iii-iv. doi: 10.3310/hta10090.
10
Chemotherapy for advanced gastric cancer.晚期胃癌的化疗
Cochrane Database Syst Rev. 2017 Aug 29;8(8):CD004064. doi: 10.1002/14651858.CD004064.pub4.
引用本文的文献
1
Molecular disruption of RAD50 sensitizes human tumor cells to cisplatin-based chemotherapy.RAD50的分子破坏使人类肿瘤细胞对基于顺铂的化疗敏感。
J Clin Invest. 2009 Jul;119(7):1974-85. doi: 10.1172/JCI33816.
本文引用的文献
1
Phase I and pharmacological studies of 5-fluorouracil administered intraperitoneally.5-氟尿嘧啶腹腔注射的I期及药理学研究
Cancer Res. 1980 Mar;40(3):567-72.
2
Treatment of women with disseminated or recurrent advanced ovarian cancer with melphalan alone in combination with 5-fluorouracil and dactinomycin or with the combination of cytoxan, 5-fluorouracil and dactinomycin.
Cancer. 1980 May 15;45(10):2529-42. doi: 10.1002/1097-0142(19800515)45:10<2529::aid-cncr2820451011>3.0.co;2-4.
3
Portal levels and hepatic clearance of 5-fluorouracil after intraperitoneal administration in humans.人腹腔内给药后5-氟尿嘧啶的门脉血药浓度及肝脏清除率
Cancer Res. 1981 May;41(5):1916-22.
4
Phase I and pharmacological studies of adriamycin administered intraperitoneally to patients with ovarian cancer.阿霉素腹腔内给药治疗卵巢癌患者的I期及药理学研究。
Cancer Res. 1982 Oct;42(10):4265-9.
5
Single-agent cis-platinum therapy for advanced ovarian cancer.顺铂单药治疗晚期卵巢癌。
Obstet Gynecol. 1981 Oct;58(4):487-96.
6
Intraperitoneal cisplatin with systemic thiosulfate protection.腹腔内注射顺铂并给予全身硫代硫酸盐保护。
Ann Intern Med. 1982 Dec;97(6):845-51. doi: 10.7326/0003-4819-97-6-845.
7
Medical Research Council study on chemotherapy in advanced ovarian cancer. Medical Research Council's Working Party on ovarian cancer.
Br J Obstet Gynaecol. 1981 Dec;88(12):1174-85. doi: 10.1111/j.1471-0528.1981.tb01194.x.
8
Epithelial carcinoma of the ovary: current strategies.卵巢上皮癌：当前策略
Ann Intern Med. 1981 Jul;95(1):98-111. doi: 10.7326/0003-4819-95-1-98.
9
Improved chemotherapy for ovarian cancer with cis-diamminedichloroplatinum and adriamycin.顺二氨二氯铂和阿霉素用于改善卵巢癌化疗效果
Cancer. 1981 May 1;47(9):2288-94. doi: 10.1002/1097-0142(19810501)47:9<2288::aid-cncr2820470931>3.0.co;2-3.
10
Acute nonlymphocytic leukemia after therapy with alkylating agents for ovarian cancer: a study of five randomized clinical trials.卵巢癌接受烷化剂治疗后发生的急性非淋巴细胞白血病：五项随机临床试验的研究
N Engl J Med. 1982 Dec 2;307(23):1416-21. doi: 10.1056/NEJM198212023072302.
Zotero 插件