小扁豆凝集素处理对不同遗传差异品系组合大鼠皮肤同种异体移植存活率的影响。
The effect of lentil lectin treatment on the survival of rat skin allografts in strain combinations with different genetic disparity.
作者信息
Hilgert I, Kristofová H, Kren V, Panczak A
出版信息
Folia Biol (Praha). 1984;30(2):104-8.
The effect of lentil lectin on the survival of skin allografts was investigated in six rat strain combinations with different genetic disparities between the donors and recipients. LCA was administered i.p. (50 mg/kg) to the recipients daily, starting with the day of transplantation (day 0) until graft rejection, except that the doses on days 1, 3, 5, 7, and 9 were given i.v. (25 mg/kg). LCA treatment was more efficient in prolongation of skin graft survival time in congenic strain combinations differing in multiple non-RT1 antigens (RT1-compatible) than in those involving RT1 disparities.
在供体和受体之间具有不同遗传差异的六种大鼠品系组合中，研究了小扁豆凝集素对同种异体皮肤移植存活的影响。从移植当天（第0天）开始，每天给受体腹腔注射LCA（50 mg/kg），直至移植排斥，不过第1、3、5、7和9天的剂量通过静脉注射（25 mg/kg）给药。与涉及RT1差异的品系组合相比，LCA处理在延长多个非RT1抗原不同的同基因品系组合（RT1兼容）中的皮肤移植存活时间方面更有效。
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