锂治疗应用于接受化疗的成人急性髓系白血病患者。
Lithium treatment in adults with acute myeloid leukemia receiving chemotherapy.
作者信息
Horns R C, Schrier S L, Greenberg P L
出版信息
Med Pediatr Oncol. 1984;12(3):169-72. doi: 10.1002/mpo.2950120305.
PMID:6374402
Abstract
To determine whether lithium can shorten chemotherapy-induced neutropenia, 35 adult patients with newly diagnosed acute myeloid leukemia undergoing initial chemotherapy were randomized either to receive oral lithium started at the time of biopsy-proven hypoplasia or to receive no lithium. This study failed to show statistically significant shortening of the duration of chemotherapy-induced neutropenia in the lithium treatment group.
摘要
为了确定锂能否缩短化疗引起的中性粒细胞减少症的持续时间，35名新诊断为急性髓系白血病且正在接受初始化疗的成年患者被随机分为两组，一组在活检证实骨髓发育不全时开始口服锂，另一组不服用锂。该研究未能显示锂治疗组化疗引起的中性粒细胞减少症持续时间有统计学意义的缩短。
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