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一只患有慢性肾小管间质性肾炎的犬的抗肾小管基底膜自身抗体。

Antitubular basement membrane autoantibody in a dog with chronic tubulointerstitial nephritis.

作者信息

Mezza L E, Seiler R J, Smith C A, Lewis R M

出版信息

Vet Pathol. 1984 Mar;21(2):178-81. doi: 10.1177/030098588402100208.

DOI:10.1177/030098588402100208
PMID:6375100
Abstract

Linear deposition of immunoglobulin G was seen by direct immunofluorescence along the tubular basement membranes in the kidney of a dog with chronic tubulointerstitial nephritis. Autoantibody eluted from the affected kidney bound to the tubular basement membrane of normal canine kidney, but not to several other normal canine basement membranes. The pathogenic significance of the autoantibody in this dog was not determined.

摘要

在一只患有慢性肾小管间质性肾炎的犬肾中,通过直接免疫荧光法可见免疫球蛋白G沿肾小管基底膜呈线性沉积。从患病肾脏洗脱的自身抗体与正常犬肾的肾小管基底膜结合,但不与其他几种正常犬基底膜结合。这只犬中自身抗体的致病意义尚未确定。

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Antitubular basement membrane autoantibody in a dog with chronic tubulointerstitial nephritis.一只患有慢性肾小管间质性肾炎的犬的抗肾小管基底膜自身抗体。
Vet Pathol. 1984 Mar;21(2):178-81. doi: 10.1177/030098588402100208.
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