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15例原发性肺恶性淋巴瘤的临床与病理表现、免疫细胞化学及超微结构研究

Primary pulmonary malignant lymphoma, clinical and pathological findings, immunocytochemical and ultrastructural studies in 15 cases.

作者信息

Le Tourneau A, Audouin J, Garbe L, Capron F, Servais B, Monges G, Payan H, Diebold J

出版信息

Hematol Oncol. 1983 Jan-Mar;1(1):49-60. doi: 10.1002/hon.2900010107.

DOI:10.1002/hon.2900010107
PMID:6376312
Abstract

Fifteen cases of primary pulmonary malignant lymphoma (M.L.) were studied using strict criteria to distinguish them from secondary pulmonary manifestations. All were M.L.'s of the lymphoid B type. Diagnosis on the basis of non specific clinical, X-ray and endoscopic findings if often difficult but can be facilitated by the systematic use of immunocytochemical and ultrastructural techniques. Their evolution is in good agreement with the prognostic data given by the Kiel-Lennert histopathological classification. 14 of the patients had M.L. of low grade malignancy; the one case of high grade malignancy was quickly fatal. A few cases appeared as a complication of a preexisting dysimmune disease (Pigeon breeder's disease, Gougerot-Sjogren disease, Liebow's lymphomatoid granulomatosis).

摘要

我们使用严格的标准对15例原发性肺恶性淋巴瘤(M.L.)进行了研究,以将它们与继发性肺部表现区分开来。所有病例均为B淋巴细胞型M.L.。基于非特异性临床、X线和内镜检查结果进行诊断通常很困难,但系统地使用免疫细胞化学和超微结构技术可能会有所帮助。它们的病程与基尔-勒纳特组织病理学分类给出的预后数据高度一致。14例患者为低级别恶性M.L.;1例高级别恶性病例很快死亡。少数病例表现为先前存在的免疫失调疾病(鸽饲养者病、古热罗-舍格伦病、利伯氏淋巴瘤样肉芽肿病)的并发症。

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