Lorenz R P, Botti J J, Chez R A, Bennett N
Obstet Gynecol. 1984 Jul;64(1):123-7.
The effect of low-dose prostaglandin E2 vaginal gel specially prepared from commercially available materials, on subsequent indicated oxytocin induction of labor, was investigated in a randomized, double-blind, placebo-controlled clinical trial. The stability of the gel after preparation was documented by radioimmunoassay in vitro. No differences between the treated and placebo groups were noted in subsequent modified Bishop scores, length of labor, use of analgesia or anesthesia, success of induction, mode of delivery, or perinatal outcome. Comparisons of this clinical trial with those previously reported are offered.
在一项随机、双盲、安慰剂对照的临床试验中，研究了由市售材料特制的低剂量前列腺素E2阴道凝胶对随后催产素引产的影响。制备后凝胶的稳定性通过体外放射免疫测定进行记录。在随后的改良Bishop评分、产程、镇痛或麻醉的使用、引产成功率、分娩方式或围产期结局方面，治疗组和安慰剂组之间未发现差异。并将该临床试验与先前报道的试验进行了比较。
