Drăgănescu N, Gîrjabu E, Antipa C, Petrescu A, Anghelescu N
Virologie. 1984 Apr-Jun;35(2):95-8.
An experimental disease could be serially propagated in the guinea pig by intracerebral inoculation of cerebrospinal fluid or brain suspensions from 8 patients with Creutzfeldt-Jakob disease (CJD). The disease, characterized by tremor, ataxia and convulsions, appeared after a long incubation period (370-420 days). Microscopic lesions and electron optic features were similar to those described in human CJD and in experimental CJD in the chimpanzee.
