Gefter W B, Epstein D M, Miller W T
Crit Rev Diagn Imaging. 1984;21(2):133-81.
This paper reviews the radiographic, clinical, pathologic, and epidemiological features of pleural and pulmonary parenchymal disorders which have been related to asbestos exposure. In particular, the following are discussed: (1) pleural plaques--radiographic detection by plain films and computed tomography, normal and abnormal densities which may mimic plaques, the 1980 ILO U/C classification, recent epidemiological data on plaques including their relationship to carcinoma and mesothelioma; (2) diffuse pleural thickening; (3) benign asbestos pleural effusions; (4) mesothelioma--emphasizing recent advances in diagnosis, staging, therapy, and prognosis; (5) parenchymal fibrosis--pathogenesis, relationship to fiber exposure, plaques, and carcinoma; (6) bronchogenic carcinoma; (7) rounded atelectasis--recent observations on its association with pleural thickening. A role of radiology in medicolegal aspects of asbestos-related disease is briefly examined.
本文综述了与石棉暴露相关的胸膜和肺实质疾病的影像学、临床、病理及流行病学特征。特别讨论了以下内容:(1)胸膜斑——平片和计算机断层扫描的影像学检测、可能模仿胸膜斑的正常和异常密度、1980年国际劳工组织的U/C分类、关于胸膜斑的近期流行病学数据,包括其与癌和间皮瘤的关系;(2)弥漫性胸膜增厚;(3)良性石棉性胸腔积液;(4)间皮瘤——着重介绍诊断、分期、治疗及预后方面的最新进展;(5)实质纤维化——发病机制、与纤维暴露、胸膜斑及癌的关系;(6)支气管源性癌;(7)圆形肺不张——关于其与胸膜增厚相关性的近期观察。简要探讨了放射学在石棉相关疾病法医学方面的作用。