Enzensberger R, Helm E B, Stille W
Dtsch Med Wochenschr. 1984 Jun 8;109(23):899-902. doi: 10.1055/s-2008-1069293.
Within a 13-year period (1970-1982) there were seen 18 cases of A-streptococcal septicaemia (age range 18-77 years), 1.3% of all septicaemia cases in this time. The portal of entry was most often a banal skin infection. Typically the disease occurred suddenly and took a fulminating course with the clinical picture of severe septicaemia. In more than half the patients septic complications occurred. Despite correct antibiotic treatment pyrexia disappeared only slowly. Four patients died of septic shock. In every case with an acute septic course and a suspicious cutaneous focus, one should think of A-streptococcal septicaemia and, if necessary, give penicillin in high dosage even before the bacterial culture result is known.
在13年期间(1970 - 1982年),共发现18例A组链球菌败血症(年龄范围为18 - 77岁),占该时期所有败血症病例的1.3%。感染途径最常见的是普通皮肤感染。该病通常突然发作,呈暴发性病程,具有严重败血症的临床表现。超过半数的患者出现了败血症并发症。尽管进行了正确的抗生素治疗,但发热仍消退缓慢。4例患者死于感染性休克。对于每一例急性败血症病程且有可疑皮肤病灶的病例,都应考虑A组链球菌败血症,如有必要,甚至在细菌培养结果出来之前就给予大剂量青霉素治疗。