Nakamura Y, Nohara M, Nakashima T, Ichikawa K, Tomita T, Kondo M, Komatsu Y, Nakashima H, Hashimoto T
Hum Pathol. 1984 Jul;15(7):651-6. doi: 10.1016/s0046-8177(84)80290-7.
Six autopsy cases of Serratia meningoencephalitis were reported. The symptoms of this infection become apparent at an early stage in neonates; the meningoencephalitis in these six cases was severe, with or without inflammatory lesions in other organs. Serratia marcescens was originally described as a nonpathogenic organism; however, it is believed that after entering the blood stream of neonates, it becomes pathogenic, especially to the central nervous system. Meningoencephalitis due to Serratia marcescens is very severe and takes a rapid and progressive course against which no antibiotics have been found effective. Prevention of this infection is therefore considered of crucial importance.
报告了6例粘质沙雷氏菌脑膜炎脑炎的尸检病例。这种感染的症状在新生儿早期就会显现；这6例中的脑膜炎脑炎病情严重，其他器官有无炎症病变。粘质沙雷氏菌最初被描述为一种非致病生物体；然而，据信在进入新生儿血流后，它会变得具有致病性，尤其是对中枢神经系统。由粘质沙雷氏菌引起的脑膜炎脑炎非常严重，呈快速进展病程，尚未发现有抗生素对其有效。因此，预防这种感染被认为至关重要。
