Olsen T, Ehlers N, Favini E
Acta Ophthalmol (Copenh). 1984 Jun;62(3):445-52. doi: 10.1111/j.1755-3768.1984.tb08424.x.
The long term results of grafting for Fuchs' endothelial dystrophy are reported in 25 patients with 33 penetrating keratoplasties, with a mean observation period of 50 months, 33% of the cases showed a visual acuity of 0.5 or better, while 42% had a visual acuity less than 0.1. The cause of visual acuity less than 0.1 was largely permanent corneal oedema, which was observed to develop in 39% of the cases. Some of the causes of oedema were accounted for by graft rejection, glaucoma and other obvious causes, but in a significant number of cases (12% of all cases), the oedema developed as a quiet, slowly progressive oedema without any obvious aetiology. It is tentatively suggested that the recurrence of oedema might be associated with the primary disease in patients with Fuchs' endothelial dystrophy.
报告了25例患者33次穿透性角膜移植治疗富克斯内皮营养不良的长期结果,平均观察期为50个月。33%的病例视力达到或优于0.5,而42%的病例视力低于0.1。视力低于0.1的主要原因是永久性角膜水肿,39%的病例出现了这种情况。水肿的一些原因是移植排斥、青光眼和其他明显原因,但在相当数量的病例中(占所有病例的12%),水肿是一种无明显病因的安静、缓慢进展的水肿。初步认为,水肿复发可能与富克斯内皮营养不良患者的原发性疾病有关。