Stevenson H C, Ochs J J, Halverson L, Oldham R K, Sherwin S A, Foon K A
Am J Med. 1984 Aug;77(2):355-8. doi: 10.1016/0002-9343(84)90720-4.
Two patients with advanced lymphoma involving the lungs that was resistant to chemotherapy had an initial excellent response to interferon therapy. After two months of stable disease, alpha interferon A therapy was discontinued, with relapse of a few months later. Both patients had extensive pulmonary involvement with relapse of the lymphoma, and both showed a dramatic response to retreatment with alpha interferon A. Unusual interferon-related pulmonary complications were observed in one patient, and their management is detailed.
两名患有晚期肺部淋巴瘤且对化疗耐药的患者对干扰素治疗最初反应良好。在病情稳定两个月后,α干扰素A治疗停药,几个月后复发。两名患者肺部均有广泛的淋巴瘤累及且复发,二者再次接受α干扰素A治疗时均显示出显著疗效。在一名患者中观察到了不寻常的与干扰素相关的肺部并发症,并详细介绍了其处理情况。