Smith J J, Dickinson J P
Lancet. 1976 Dec 18;2(7999):1336-7. doi: 10.1016/s0140-6736(76)91978-4.
An established method of investigating total surface charge on particulate materials has been applied to the detection of changes in surface charge on macrophages which are induced by supernatants from the interaction of sensitised lymphocytes and appropriate antigen. The method was studied as an alternative to the established but problematical macrophage-electrophoretic-mobility (M.E.M.) test for detecting such changes. This preliminary investigation suggests that the results from subjects with and without malignant disease differ significantly.
一种已确立的研究颗粒材料总表面电荷的方法已被应用于检测巨噬细胞表面电荷的变化，这些变化是由致敏淋巴细胞与适当抗原相互作用产生的上清液所诱导的。该方法作为检测此类变化的既定但有问题的巨噬细胞电泳迁移率（M.E.M.）测试的替代方法进行了研究。这项初步研究表明，患有和未患有恶性疾病的受试者的结果存在显著差异。
