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诱导蟾蜍膀胱中钠离子通过主动转运途径发生逆向流动。

Induction of reverse flow of Na+ through the active transport pathway in toad urinary bladder.

作者信息

Dawson D C, Al-Awquati Q

出版信息

Biochim Biophys Acta. 1978 Apr 4;508(2):413-7. doi: 10.1016/0005-2736(78)90343-7.

DOI:10.1016/0005-2736(78)90343-7
PMID:638149
Abstract

When active Na+ transport across the toad urinary bladder was abolished by ouabain, a 'reversed' short circuit current could be induced by an Na+ concentration gradient. This reversed current was increased by vasopressin and inhibited by amiloride and appears to represent net Na+ movement 'backwards' through epithelial cells which normally participate in active Na+ transport across the bladder.

摘要

当哇巴因消除蟾蜍膀胱的主动钠转运时,钠浓度梯度可诱导出“反向”短路电流。这种反向电流会因血管升压素而增加,因阿米洛利而受到抑制,它似乎代表钠通过正常参与膀胱主动钠转运的上皮细胞“反向”净移动。

相似文献

1
Induction of reverse flow of Na+ through the active transport pathway in toad urinary bladder.诱导蟾蜍膀胱中钠离子通过主动转运途径发生逆向流动。
Biochim Biophys Acta. 1978 Apr 4;508(2):413-7. doi: 10.1016/0005-2736(78)90343-7.
2
Amiloride: a potent inhibitor of sodium transport across the toad bladder.氨氯地平:蟾蜍膀胱钠转运的强效抑制剂。
J Physiol. 1968 Mar;195(2):317-30. doi: 10.1113/jphysiol.1968.sp008460.
3
Relationship of transient electrical properties to active sodium transport by toad urinary bladder.蟾蜍膀胱瞬态电特性与活性钠转运的关系。
J Membr Biol. 1980 Jan 31;52(1):25-35. doi: 10.1007/BF01869003.
4
Epithelial cell electrolytes in relation to transepithelial sodium transport across toad urinary bladder.上皮细胞电解质与蟾蜍膀胱跨上皮钠转运的关系。
J Membr Biol. 1978;40 Spec No:247-60. doi: 10.1007/BF02026009.
5
Effect of ADH, aldosterone, ouabain, and amiloride on toad bladder epithelial cells.抗利尿激素、醛固酮、哇巴因和氨氯吡脒对蟾蜍膀胱上皮细胞的作用。
Am J Physiol. 1972 May;222(5):1071-4. doi: 10.1152/ajplegacy.1972.222.5.1071.
6
Dependence of the driving force of the sodium pump on rate of transport.
Am J Physiol. 1977 May;232(5):448-54. doi: 10.1152/ajprenal.1977.232.5.F448.
7
Effects of active sodium transport on current-voltage relationship of toad bladder.主动钠转运对蟾蜍膀胱电流-电压关系的影响。
Am J Physiol. 1970 Jul;219(1):234-45. doi: 10.1152/ajplegacy.1970.219.1.234.
8
Inhibition by ammonium of sodium transport across isolated toad bladder.
Am J Physiol. 1971 Jun;220(6):1651-9. doi: 10.1152/ajplegacy.1971.220.6.1651.
9
Effect of aldosterone on the sodium content and energy metabolism of epithelial cells of the toad urinary bladder.醛固酮对蟾蜍膀胱上皮细胞钠含量及能量代谢的影响。
J Steroid Biochem. 1972 Feb;3(2):137-41. doi: 10.1016/0022-4731(72)90043-x.
10
Effects of 2-deoxy-D-glucose, amiloride, vasopressin, and ouabain on active conductance and ENa in the toad bladder.2-脱氧-D-葡萄糖、氨氯吡脒、血管升压素和哇巴因对蟾蜍膀胱主动电导和上皮钠通道的影响。
J Membr Biol. 1976 Aug 26;28(2-3):121-42. doi: 10.1007/BF01869693.

引用本文的文献

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Sodium flux ratio through the amiloride-sensitive entry pathway in frog skin.蛙皮中通过氨氯地平敏感的进入途径的钠通量比率。
J Gen Physiol. 1983 May;81(5):667-85. doi: 10.1085/jgp.81.5.667.
2
Passive cation permeability of turtle colon: evidence for a negative interaction between intracellular sodium and apical sodium permeability.
Pflugers Arch. 1985 Jan;403(1):82-9. doi: 10.1007/BF00583286.
3
Sodium transport in the hen lower intestine. induction of sodium sites in the brush border by a low sodium diet.母鸡下肠道中的钠转运。低钠饮食对刷状缘钠位点的诱导作用。
J Physiol. 1979 Mar;288:449-66.