Hashimoto K, Takahashi S, Lee R G, Krull E A
J Am Acad Dermatol. 1984 Sep;11(3):447-54. doi: 10.1016/s0190-9622(84)70189-7.
A new case of congenital self-healing reticulohistiocytosis was studied with S-100 antibody and electron microscopy. Many tumor cells were S-100-positive and contained Langerhans cell (LC) granules and concentrically laminated dense bodies. Octopus-like bodies and wormlike bodies were also found. The formation of LC granules at the cytomembrane was frequently found, not only between the cytomembrane and its own villi, but also between the cytomembranes of adjoining cells. These findings strongly support the cytomembrane origin of LC granules in general.
采用S-100抗体和电子显微镜对1例先天性自愈性网状组织细胞增生症新病例进行了研究。许多肿瘤细胞S-100阳性，含有朗格汉斯细胞（LC）颗粒和同心层状致密小体。还发现了章鱼样小体和蠕虫样小体。不仅在细胞膜与其自身绒毛之间，而且在相邻细胞的细胞膜之间，经常发现细胞膜处有LC颗粒形成。这些发现有力地支持了一般情况下LC颗粒的细胞膜起源。
