Zierler R E, Bandyk D F, Thiele B L
J Vasc Surg. 1984 Jan;1(1):73-83.
The use of operative arteriography during carotid endarterectomy facilitates identification and correction of technical errors. Although arteriography is the standard for assessing surgical results, it prolongs the operation and may increase the overall risk. The purpose of this study was to evaluate pulsed Doppler spectral analysis and arteriography as methods of intraoperative assessment. Operative arteriography was performed in 150 consecutive carotid endarterectomies. In 50 of these cases a sterile 20 MHz pulsed Doppler probe and real-time spectrum analyzer were used to evaluate internal carotid velocity patterns before and after endarterectomy. Operative arteriograms were normal in 127 cases, whereas abnormalities were noted in 16 internal and seven external carotid arteries. Thirteen of the arteriographic defects were considered minor and accepted. Major defects requiring immediate repair occurred in eight (5%) internal and two external carotid arteries. In the 50 cases assessed by both techniques, seven internal carotid arteries had mild flow disturbances both before and after endarterectomy, whereas 38 of the remaining 43 arteries showed improvement in spectral characteristics after endarterectomy. In two patients who failed to show improvement on the initial postendarterectomy evaluation, operative arteriography demonstrated residual defects that required immediate repair. No other technical errors were encountered, and there were no perioperative deaths or neurologic complications in the 150 operations. Intraoperative assessment by pulsed Doppler spectral analysis is a safe, rapid, and accurate method for detecting technical errors during carotid endarterectomy. The high sensitivity of this method (no false negative assessments) makes it an ideal screening test to be used for selection of patients for operative arteriography. By indicating when a technical error is most likely, this approach precludes the need for routine operative arteriography.
在颈动脉内膜切除术期间使用术中动脉造影有助于识别和纠正技术失误。尽管动脉造影是评估手术结果的标准方法,但它会延长手术时间并可能增加总体风险。本研究的目的是评估脉冲多普勒频谱分析和动脉造影作为术中评估方法的效果。对连续150例颈动脉内膜切除术患者进行了术中动脉造影。在其中50例病例中,使用无菌20兆赫脉冲多普勒探头和实时频谱分析仪在动脉内膜切除术前和术后评估颈内动脉血流速度模式。127例患者的术中动脉造影结果正常,而16例颈内动脉和7例颈外动脉出现异常。其中13处动脉造影缺陷被认为是轻微的并被接受。需要立即修复的主要缺陷出现在8例(5%)颈内动脉和2例颈外动脉。在通过两种技术评估的50例病例中,7例颈内动脉在动脉内膜切除术前和术后均有轻度血流紊乱,而其余43条动脉中的38条在动脉内膜切除术后频谱特征有所改善。在2例术后初始评估未显示改善的患者中,术中动脉造影显示存在需要立即修复的残余缺陷。未遇到其他技术失误,150例手术中无围手术期死亡或神经并发症。术中通过脉冲多普勒频谱分析进行评估是一种安全、快速且准确的检测颈动脉内膜切除术期间技术失误的方法。该方法的高灵敏度(无假阴性评估)使其成为用于选择进行术中动脉造影患者的理想筛查测试。通过指出何时最可能出现技术失误,这种方法无需常规术中动脉造影。