Jernigan W R, Fulton R L, Hamman J L, Miller F B, Mani S S
Surgery. 1984 Nov;96(5):831-8.
Routine operative angiography was performed during a 14 1/2-year period ending June 1982, during which 603 consecutive carotid endarterectomies were performed. For the purpose of standardization, a functional classification of stroke in terms of severity was established: class I--minimal, class II--moderate, class III--marked, class IV--severe, and class V--coma or death. Patients were analyzed to determine the cause of the stroke, the severity of the stroke, and the efficacy of routine operative angiography in reducing the incidence of perioperative stroke caused by technical error. Perioperative stroke occurred in 18 patients (2.9%), with only one having been caused by technical error. Fifteen patients underwent revision of the endarterectomy before wound closure because of unsatisfactory operative angiography results. None of the patients developed permanent neurologic deficits. Permanent perioperative neurologic deficits resulted from embolization (six patients), hypertensive episodes with cerebral hemorrhage (three patients), conversion of ischemic to hemorrhagic infarcts (two patients), spontaneous thrombosis (one patient), clamp ischemia (two patients), and other factors (three patients). Nine patients died, two of myocardial infarction and seven of stroke, for a combined mortality and morbidity rate of 3.3%. There were three class II, five class III, two class IV, and eight class V strokes that were determined to be related to the procedure. In this series stroke may have been prevented in 15 patients who underwent revision of the endarterectomy because of an unacceptable technical error demonstrated on operative angiography.
在截至1982年6月的14年半时间里进行了常规手术血管造影,在此期间连续进行了603例颈动脉内膜切除术。为了标准化,根据严重程度建立了卒中功能分类:I级——轻微,II级——中度,III级——显著,IV级——严重,V级——昏迷或死亡。对患者进行分析以确定卒中原因、卒中严重程度以及常规手术血管造影在降低技术失误导致的围手术期卒中发生率方面的疗效。18例患者(2.9%)发生围手术期卒中,其中仅1例由技术失误引起。15例患者因手术血管造影结果不理想在伤口缝合前接受了内膜切除术修复。所有患者均未出现永久性神经功能缺损。永久性围手术期神经功能缺损由栓塞(6例患者)、高血压伴脑出血发作(3例患者)、缺血性梗死转变为出血性梗死(2例患者)、自发性血栓形成(1例患者)、夹闭缺血(2例患者)以及其他因素(3例患者)导致。9例患者死亡,2例死于心肌梗死,7例死于卒中,总死亡率和发病率为3.3%。确定有3例II级、5例III级、2例IV级和8例V级卒中与手术相关。在本系列中,15例因手术血管造影显示不可接受的技术失误而接受内膜切除术修复的患者,其卒中可能已得到预防。