Weidle E G, Thiel H J
Klin Monbl Augenheilkd. 1984 Jun;184(6):520-8. doi: 10.1055/s-2008-1054544.
Over a period of 2 1/2 years penetrating keratoplasty was performed on 11 patients suffering from fulminating bacterial infection of the cornea at the florid stage, in 4 cases with perforation. Therapeutic keratoplasty is indicated for hypopyon ulcer and corneal abscess in 3 situations: (1) when the infected cornea perforates spontaneously; (2) when perforation threatens, even though the symptoms of the infection may be regressive; (3) when medication fails to change the course. Early operative intervention is to be recommended in each case. The aim of therapeutic keratoplasty is to eliminate the dangerous pathologic process in the cornea and to shorten the duration of the condition. This can be achieved with impressive speed. In some cases a primary result is attainable which is visually satisfactory and permanent, as was the case with 2 patients in the group described in this paper; as is to be expected, however, follow-up operations are often necessary and offer a second opportunity of restoring vision as well.
在两年半的时间里，对11例处于角膜细菌感染急性期、其中4例已穿孔的患者实施了穿透性角膜移植术。治疗性角膜移植适用于以下3种情况下的前房积脓性溃疡和角膜脓肿：（1）感染的角膜自发穿孔时；（2）即使感染症状可能在消退，但穿孔即将发生时；（3）药物治疗未能改变病程时。每种情况均建议早期进行手术干预。治疗性角膜移植的目的是消除角膜中的危险病理过程并缩短病程。这可以以惊人的速度实现。在某些情况下，可以获得初步结果，视觉效果令人满意且持久，本文所述组中的2例患者就是如此；然而，可以预料的是，通常需要进行后续手术，这也为恢复视力提供了第二次机会。
