Kucera H, Wagner G, Weghaupt K
Onkologie. 1984 Aug;7(4):244-8. doi: 10.1159/000215449.
A report is given about the experience in preoperative, nonfractionated high-dose iridium-192 irradiation in cases of carcinoma of the cervix uteri. A few days prior to radical hysterectomy a dose of 20 Gy (in 2 cm distance) was applied locally by means of a loop-applicator (afterloading technique, Buchler). In cases without postoperative irradiation severe vaginal necroses, in cases with postoperative irradiation severe local and peripheral lesions were observed. In 8 of 10 cases irradiated pre- and postoperatively, another surgical intervention was necessary because of complications in the urinary or intestinal tract. This publication is presented as a warning for preoperative high-dose irradiation with 20 Gy applied locally in cases of carcinoma of the cervix uteri.
本文报告了子宫颈癌术前非分次大剂量铱-192照射的经验。在根治性子宫切除术术前几天，通过环形施源器（后装技术，布赫勒）在局部给予20 Gy（距离2 cm处）的剂量。在未进行术后放疗的病例中观察到严重的阴道坏死，在进行术后放疗的病例中观察到严重的局部和周围病变。在10例接受术前和术后放疗的病例中，有8例因泌尿系统或肠道并发症而需要再次进行手术干预。本文旨在对子宫颈癌病例局部应用20 Gy术前大剂量照射发出警示。
