VanHale H M, Rogers R S
Cutis. 1984 Sep;34(3):284-8, 290.
Tissue from seventeen patients with recurrent aphthous ulcers was studied by light and immunofluorescent microscopy to characterize changes in the inflammatory infiltrate throughout the evolution of the lesion. Enzyme histochemical studies and immunoperoxidase stains for immunoglobulin revealed that monocytes and histiocytes form a large proportion of the infiltrate in the early phase of the ulcer and that most lymphoid cells present are of T-cell origin. Immunoglobulin-bearing lymphocytes and plasma cells are sparse at all stages. Direct immunofluorescent studies were frequently positive; however, no consistent pattern was noted.
对17例复发性阿弗他溃疡患者的组织进行了光镜和免疫荧光显微镜检查，以描述病变演变过程中炎症浸润的变化特征。酶组织化学研究和免疫球蛋白免疫过氧化物酶染色显示，单核细胞和组织细胞在溃疡早期浸润中占很大比例，且存在的大多数淋巴细胞起源于T细胞。携带免疫球蛋白的淋巴细胞和浆细胞在所有阶段都很稀少。直接免疫荧光研究经常呈阳性；然而，未观察到一致的模式。
