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佩特兹氏病

Perthes' disease.

作者信息

Klisić P J

出版信息

Int Orthop. 1984;8(2):95-102. doi: 10.1007/BF00265831.

Abstract

Perthes' disease may be regarded as a generalised disorder of cartilage development in which there is a particular predisposition for repeated episodes of infarction in the proximal femoral epiphysis. The resulting deformation of the head is due to collapse of the ossific nucleus and irregular growth of the cartilage. The shape of the epiphysis is determined by the pressure of the surrounding structures. The most ominous factors determining prognosis are onset in the older child, epiphysial protrusion, extensive involvement of the epiphysis and arrest of subcapital growth. The overall prognosis is determined by the quality of preservation of the sphericity of the head, with maldevelopment leading to osteoarthritis. The aim of treatment is to achieve sphericity by containing the epiphysis within the acetabulum. A uniform regime of management cannot be recommended for all patients. Prolonged weight relief in containment appears to be the most satisfactory method of treatment in those with a pour prognosis. Operation is necessary to provide containment in the presence of ephiphyseal protrusion, and may also shorten the length of treatment in some younger patients. In the majority of young children the use of abduction braces which permit walking is recommended. In children with a minor degree of involvement a short period of bedrest may be all that is required. Overtreatment of young children should be avoided, as should undertreatment in the older age groups.

摘要

佩特兹病可被视为一种软骨发育的全身性疾病,其中股骨近端骨骺特别容易反复发生梗死。由此导致的股骨头变形是由于骨化核塌陷和软骨生长不规则所致。骨骺的形状由周围结构的压力决定。决定预后的最不利因素是患儿年龄较大时发病、骨骺突出、骨骺广泛受累以及股骨头下生长停滞。总体预后取决于股骨头球形度的保留质量,发育不良会导致骨关节炎。治疗的目的是通过将骨骺包容在髋臼内来实现球形度。不能为所有患者推荐统一的治疗方案。对于预后较差的患者,在包容治疗中长时间减轻体重似乎是最令人满意的治疗方法。在骨骺突出的情况下,手术是实现包容所必需的,在一些较年轻的患者中还可能缩短治疗时间。对于大多数幼儿,建议使用允许行走的外展支具。对于受累程度较轻的儿童,可能只需短期卧床休息。应避免对幼儿过度治疗,对年龄较大的儿童也应避免治疗不足。

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