Kopf A W, Kripke M L, Stern R S
J Am Acad Dermatol. 1984 Oct;11(4 Pt 1):674-84. doi: 10.1016/s0190-9622(84)70225-8.
The incidence and mortality rates of malignant melanoma in Caucasians are increasing rapidly in many countries worldwide. Considerable circumstantial evidence suggests that exposure to solar radiation may play a role in this substantial rise in malignant melanoma. This evidence comes primarily from epidemiologic studies and from the identification of susceptible phenotypes. Despite the increasing data that implicate sunlight as an important factor in the development of certain types of malignant melanomas in humans, the role of solar electromagnetic radiation in the pathogenesis of human malignant melanomas is yet to be determined.
在全球许多国家，白种人中恶性黑色素瘤的发病率和死亡率正在迅速上升。大量间接证据表明，暴露于太阳辐射可能在恶性黑色素瘤的大幅增加中起作用。这一证据主要来自流行病学研究以及易感表型的鉴定。尽管越来越多的数据表明阳光是人类某些类型恶性黑色素瘤发生发展的重要因素，但太阳电磁辐射在人类恶性黑色素瘤发病机制中的作用仍有待确定。
