Fabre F, Boulet A, Roman H
Mol Gen Genet. 1984;195(1-2):139-43. doi: 10.1007/BF00332736.
In the Saccharomyces cerevisiae mitotic cycle, the timing of radiation-induced gene conversion has been studied using thermosensitive cell division cycle mutants. The cells were found to perform conversion at different G1 or post-replication steps. A lower yield in induction is found during the G2 phase and is explained by the competition for recombinational repair between sister chromatids and homologous chromosomes. The results are discussed in relation to repair.
在酿酒酵母的有丝分裂周期中,利用温度敏感型细胞分裂周期突变体研究了辐射诱导基因转换的时间。发现细胞在不同的G1期或复制后步骤进行转换。在G2期诱导产量较低,这是由于姐妹染色单体和同源染色体之间在重组修复方面的竞争所致。结合修复对结果进行了讨论。