Geier G E, Gashti E N, Houin H P, Johnloz D, Madura J A
Am Surg. 1984 Nov;50(11):617-22.
Villous adenoma of the duodenum (VAD) is a rare tumor occurring predominantly in middle-aged adults and most commonly found in the second portion of the duodenum. The authors describe five cases of VAD and discuss histologic criteria for diagnosis of malignant transformation. Diagnostically, more than 90 per cent of all lesions are identified by upper gastrointestinal series and endoscopy. Treatment of choice for benign lesions is local excision, while malignant lesions should be treated with more extensive resection. In situ carcinoma in the elderly should be managed on an individual basis.
十二指肠绒毛状腺瘤（VAD）是一种罕见肿瘤，主要发生于中年成年人，最常见于十二指肠第二部。作者描述了5例VAD病例，并讨论了恶性转化的组织学诊断标准。在诊断方面，超过90%的病变可通过上消化道造影和内镜检查发现。良性病变的首选治疗方法是局部切除，而恶性病变则应进行更广泛的切除。老年人的原位癌应个体化处理。
