Miller D R, Egbert R M, Braunstein P
Arch Surg. 1984 Nov;119(11):1233-7. doi: 10.1001/archsurg.1984.01390230005001.
We retrospectively reviewed the clinical data of 17 selected patients who underwent hepatobiliary imaging studies using technetium Tc 99m iprofenin that demonstrated acute complete common bile duct obstruction, and who also had a temporally related ultrasonographic study of the hepatobiliary tree. We compared the accuracy of the two methods in the detection of common duct obstruction. The average duration of symptoms was 2.9 days. Serum bilirubin levels averaged 3.3 mg/dL and the average alkaline phosphatase level was 336 mg/dL. The serum amylase level was elevated in only three patients. Ultrasonographic dilatation of the ductal structures was present in seven (41%) of 17 patients; 88% of the patients had other manifestations of gallbladder disease on ultrasonography--either cholelithiasis, dilatation of the gallbladder, or wall thickening. Of 15 patients who were operated on, 11 had stones impacted at the ampulla of Vater. There was a poor correlation of ultrasonographic ductal dilatation and operative findings of ductal dilatation. This study shows the superiority of nuclear imaging over ultrasonography in the early detection of acute, common bile duct obstruction.
我们回顾性分析了17例患者的临床资料,这些患者接受了使用锝Tc 99m依普罗芬进行的肝胆成像研究,结果显示存在急性完全性胆总管梗阻,并且他们还进行了与时间相关的肝胆管超声检查。我们比较了两种方法在检测胆总管梗阻方面的准确性。症状的平均持续时间为2.9天。血清胆红素水平平均为3.3mg/dL,碱性磷酸酶平均水平为336mg/dL。仅3例患者血清淀粉酶水平升高。17例患者中有7例(41%)存在超声检查显示的胆管结构扩张;88%的患者在超声检查中有胆囊疾病的其他表现——要么是胆结石、胆囊扩张,要么是胆囊壁增厚。在接受手术的15例患者中,11例在 Vater壶腹处有结石嵌顿。超声检查显示的胆管扩张与手术中胆管扩张的发现相关性较差。这项研究表明,在急性胆总管梗阻的早期检测中,核成像优于超声检查。