O'Brien C J, Harris J P, May J
Br J Plast Surg. 1984 Oct;37(4):596-601. doi: 10.1016/0007-1226(84)90156-5.
A study was made to evaluate the accuracy of Doppler ultrasound in assessing patency in experimental microvascular grafts in rats. In 20 animals, pre-operative assessment produced a phasic wave form and audio signal consistent with arterial flow when the Doppler probe was placed over the groin crease. Ten animals then had a sham operation exposing the femoral vessels through a groin crease incision. The remaining 10 had a 10 mm segment of femoral artery excised to simulate an occluded graft. These animals were re-assessed 18 to 20 days later and the wave form and audio signal of arterial flow were detectable in the sham operated animals with the probe placed below the groin incision. No signal was elicited at this site in the animals whose femoral arteries had been excised. When these principles were applied to 20 rats with microvenous grafts and 20 with 1 mm PTFE grafts in the femoral artery we predicted graft patency with 100% accuracy. This non-invasive technique is inexpensive and highly accurate.
开展了一项研究，以评估多普勒超声在评估大鼠实验性微血管移植物通畅情况方面的准确性。在20只动物中，术前评估时，当多普勒探头置于腹股沟皱襞上方时，产生了与动脉血流一致的搏动波形和音频信号。然后，10只动物接受了假手术，通过腹股沟皱襞切口暴露股血管。其余10只动物切除了10毫米长的股动脉段，以模拟闭塞的移植物。18至20天后对这些动物进行重新评估，在假手术动物中，将探头置于腹股沟切口下方时，可检测到动脉血流的波形和音频信号。在股动脉已被切除的动物的该部位未引出信号。当将这些原理应用于20只接受股静脉移植物的大鼠和20只接受1毫米聚四氟乙烯股动脉移植物的大鼠时，我们预测移植物通畅情况的准确率为100%。这种非侵入性技术价格低廉且高度准确。
