[Hormonal function of islands of Langerhans in diabetes mellitus].

Some hormonal characteristics were examined in 23 patients with diabetes mellitus. Of these, 7 patients had an insulin-dependent and 19 an insulin-independent disease pattern. It was demonstrated that after treatment the level of IRI and c-peptide remained within normal. The levels of glucagon and somatostatin were considerably elevated and did not show any noticeable decrease after treatment. Both groups manifested an increased number of antibodies against insulin, with that number remaining virtually unchanged after treatment.