Leslie K E, Doig P A, Bosu W T, Curtis R A, Martin S W
Can J Comp Med. 1984 Oct;48(4):354-9.
The effects of gonadotrophin releasing hormone (GnRH) on the reproductive performance of dairy cows with retained placenta were studied. Three hundred and seventy-eight cows diagnosed as having retained placenta received intramuscular injections of either 2 mL sterile water or 200 micrograms of GnRH in 2 mL sterile water between day 8 and day 14 postpartum. Rectal palpation was performed at the time of treatment and ten to 20 days after treatment in order to determine the rate of uterine involution. Thereafter, monthly rectal examinations were carried out until insemination. Pregnancy diagnosis was made by rectal palpation at 40 days or more after breeding. Using the entire experimental population, there were no significant differences between GnRH-treated and control cows for the rate of uterine involution, the occurrence of reproductive problems, the interval from parturition to first observed estrus, the interval from parturition to first insemination, the interval from parturition to conception, the number of services per conception, the total number of services per cow regardless of conception and the incidence of culling for infertility. When the data for herds in which breeding began earlier in the postpartum period (herds having a mean less than or equal to 80 days from parturition to first service for retained placenta cows) were considered, the GnRH treatment resulted in a significantly shorter (p less than or equal to 0.01) calving to conception interval as compared to control cows. Also, there was a significant reduction (p less than or equal to 0.05) in the total number of services per cow regardless of conception and a significant reduction in the interval from parturition to first service.(ABSTRACT TRUNCATED AT 250 WORDS)
研究了促性腺激素释放激素(GnRH)对患有胎盘滞留的奶牛繁殖性能的影响。378头被诊断为胎盘滞留的奶牛在产后第8天至第14天期间,肌肉注射2毫升无菌水或2毫升无菌水中含200微克GnRH。在治疗时以及治疗后10至20天进行直肠触诊,以确定子宫复旧率。此后,每月进行直肠检查直至配种。在配种后40天或更长时间通过直肠触诊进行妊娠诊断。在整个实验群体中,GnRH处理组和对照组奶牛在子宫复旧率、繁殖问题发生率、从分娩到首次观察到发情的间隔、从分娩到首次配种的间隔、从分娩到受孕的间隔、每次受孕的输精次数、每头奶牛无论是否受孕的输精总数以及因不育而淘汰的发生率方面均无显著差异。当考虑产后早期开始配种的牛群(胎盘滞留奶牛从分娩到首次输精的平均天数小于或等于80天的牛群)的数据时,与对照组奶牛相比,GnRH处理使产犊到受孕的间隔显著缩短(p≤0.01)。此外,每头奶牛无论是否受孕的输精总数显著减少(p≤0.05),从分娩到首次输精的间隔也显著缩短。(摘要截短至250字)