Barth K H, Mertens M A
Invest Radiol. 1984 Nov-Dec;19(6 Suppl):S323-5. doi: 10.1097/00004424-198411001-00012.
A diatrizoate compound (Renografin-76) and low osmolality Hexabrix were compared in a double-blind study of 50 adults undergoing arteriographic examination. Subjective and objective assessment of pain reaction for each contrast injection rated lower overall for Hexabrix. Discomfort associated with Renografin was greatest for injections into extremity arteries. Hexabrix showed the least change in serum osmolality. No impairment of renal function was evidenced with either contrast media. No difference in the angiographic quality of the control agents was noted.
在一项针对50名接受动脉造影检查的成年人的双盲研究中，对泛影葡胺化合物（泛影葡胺-76）和低渗性六溴酚进行了比较。每次注射造影剂后，对疼痛反应的主观和客观评估显示，六溴酚的总体评分较低。与泛影葡胺相关的不适在注射到四肢动脉时最为明显。六溴酚的血清渗透压变化最小。两种造影剂均未显示肾功能受损。对照剂的血管造影质量没有差异。
