Demoulin A, Schaaps J P, Lambotte R
J Gynecol Obstet Biol Reprod (Paris). 1984;13(6):635-42.
Follicular growth and ovulation may be estimated by various techniques: basal body temperature charts, cervical score and vaginal smears examination, gonadal steroids or gonadotropin measurement and more recently, pelvic echography. Echographic monitoring permits the determination of the number and the size of ovarian follicles and the prediction of the time of ovulation. 1065 cycles of patients consulting in an artificial insemination with donor semen program have been analyzed. Follicular growth is superimposable in spontaneous and hMG-induced cycles, but clomiphene treatment leads to the formation of larger follicles. Only one dominant follicle (greater than or equal to 15 mm) is generally observed in spontaneous cycles; multiple dominant follicles are visualized in respectively 11,8 and 24,3% cycles treated with either hMG or clomiphene. These follicles are localized in only one ovary in half of the cases. Consecutive monitoring in several cycles shows that the ovaries do not alternate systematically. While this type of monitoring does permit a reduction in the number of straws used, it does not improve the success rate of artificial insemination.
基础体温图表、宫颈评分和阴道涂片检查、性腺甾体激素或促性腺激素测量,以及最近的盆腔超声检查。超声监测可确定卵巢卵泡的数量和大小,并预测排卵时间。对参与供精人工授精项目的患者的1065个周期进行了分析。自发周期和人绝经期促性腺激素(hMG)诱导周期中的卵泡生长情况相似,但克罗米芬治疗会导致形成更大的卵泡。在自发周期中通常仅观察到一个优势卵泡(大于或等于15毫米);在接受hMG或克罗米芬治疗的周期中,分别有11.8%和24.3%的周期可见多个优势卵泡。这些卵泡在半数病例中仅位于一侧卵巢。对多个周期进行连续监测表明,卵巢并非有规律地交替排卵。虽然这种监测确实可以减少精子的使用数量,但并未提高人工授精的成功率。