Tanii T, Hamada T
Dermatologica. 1984;169(6):354-8. doi: 10.1159/000249627.
A 2-year-old girl having a bald nodule on the scalp is reported. The tumor was circular, hemispherically elevated and had a dull reddish color. Roentgenologic studies revealed a defect of the underlying skull bone, and spina bifida occulta on the first and second sacral vertebra were found. Craniotomy was carried out. The tumor extended into the falx cerebri and reached to the tentorium cerebelli, and was not connected with the cerebrum. Histological examination showed insular brain tissue containing glial cells in the lower dermis. Around this tissue, there seemed to be vascular leptomeninges with numerous melanocytes and thickened fibrous elements, probably dura. From these findings, this case was diagnosed as a variant of encephalomeningocele, and as melanocytes physiologically exist on the leptomeninges, melanocytes in an encephalomeningocele may diagnostically identify the leptomeninges.
报告了一名2岁女童，其头皮上有一个秃发性结节。肿瘤呈圆形，半球形隆起，颜色为暗红色。放射学检查显示颅骨骨缺损，并发现第一和第二骶椎隐性脊柱裂。进行了开颅手术。肿瘤延伸至大脑镰并到达小脑幕，与大脑不相连。组织学检查显示在真皮下部有包含神经胶质细胞的岛状脑组织。在该组织周围，似乎有血管性软脑膜，有大量黑素细胞和增厚的纤维成分，可能是硬脑膜。根据这些发现，该病例被诊断为脑膨出的一种变体，并且由于黑素细胞在生理上存在于软脑膜上，脑膨出中的黑素细胞在诊断上可识别软脑膜。
