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[激光辐射与血卟啉联合作用对鼠伤寒沙门氏菌(TA 100)菌株的生物学效应]

[Biological effects of the combined action of laser radiation and hematoporphyrin on a strain of Salmonella typhimurium (TA 100)].

作者信息

Curci E, Pasquetto N, Giordano D

出版信息

G Batteriol Virol Immunol. 1983 Jul-Dec;76(7-12):290-9.

PMID:6397389
Abstract

The AA. have studied biological effects of Laser radiation and Haematoporphyrin (HPD) on Salmonella typhimurium TA 100 strain. Their results do not show a growth of letal effect that they demonstrated on antecedent trials, only dependent from Laser radiation. Nome mutagenetic effect was demonstrated. They think that HPD is not capable of binding or penetrating in bacterial cell owing to complexity of bacterial capsule and wall; therefore HPD can not increase Laser radiation effect, though its photodynamic action.

摘要

研究人员研究了激光辐射和血卟啉(HPD)对鼠伤寒沙门氏菌TA 100菌株的生物学效应。他们的结果并未显示出如先前试验中仅由激光辐射所证明的致死效应的增长。未显示出任何诱变效应。他们认为,由于细菌荚膜和细胞壁的复杂性,HPD无法结合或穿透细菌细胞;因此,尽管HPD具有光动力作用,但它无法增强激光辐射的效应。

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