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[超致死剂量磷胺中毒并经多利宁治疗的猫的肌电电位变化]

[Changes in the electromyographic potentials in cats poisoned with superlethal doses of phosdrin and treated with doline].

作者信息

Mashkova D, Kotev G, Kolchev Kh

出版信息

Eksp Med Morfol. 1978;17(1):32-6.

PMID:639745
Abstract

The authors carried out studies on 10 cats, anesthetized by urethane, under atropine protection and under the conditions of artificial respiration and examined the influence of therapeutic antidote of phosphorganic pesticides-Doline on the induced eletromyographic activity during total neuro-muscular block, induced by superlethal doses of phosphadrine. It was established that superlethal doses of phosphadrine induced total block of electropotentials in neuro-muscular conduction of the peripheral musculature, which was removed immediately after venous and muscular administration of the antidote Doline.

摘要

作者对10只经氨基甲酸乙酯麻醉、在阿托品保护及人工呼吸条件下的猫进行了研究,考察了有机磷农药治疗解毒剂——多磷嗪对由超致死剂量的磷胺诱发的完全神经肌肉阻滞期间诱发肌电活动的影响。结果表明,超致死剂量的磷胺可导致外周肌肉组织神经肌肉传导中电位的完全阻滞,在静脉和肌肉注射解毒剂多磷嗪后,这种阻滞立即解除。

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