Koslowski J P, Serve L, Bouygues D, Nougue J, Oksman F
Rev Fr Gynecol Obstet. 1984 Jan;79(1):59-62.
The authors report a case of bullous dermatosis developing at 38 weeks of amenorrhoea in a para II. The newborn infant developed a skin rash 3 days after birth. Direct immunofluorescent study of skin biopsies showed the presence of a very small amount of IgG and a very large amount of complement fixed to the basal membrane. Tests for the presence of Herpes gestationis factor in maternal and child blood by immunofluorescence to anti-complement were negative. Tests for anti-epidermal antibodies by indirect immunofluorescence in the serum were also negative, for both anti-basal membrane antibodies as well as anti-intercellular substance antibodies.
作者报告了一例经产妇在闭经38周时发生大疱性皮肤病的病例。新生儿在出生后3天出现皮疹。皮肤活检的直接免疫荧光研究显示,有极少量的IgG和大量补体附着于基底膜。通过免疫荧光抗补体法检测母婴血液中妊娠疱疹因子均为阴性。血清间接免疫荧光法检测抗表皮抗体,包括抗基底膜抗体和抗细胞间物质抗体也均为阴性。