Tandu-Umba N F, Ntabona B, Mputu L
Rev Fr Gynecol Obstet. 1984 Feb;79(2):131-5.
This retrospective study over an 11-year period revealed 79 cases of visible congenital malformations in a total of 64,777 deliveries (prevalence 1.2%). No aetiological feature was demonstrated. In contrast to data from the literature, the maternal age most involved was between 20 and 35 years and the pregnancy affected most often appeared to be the first. A past history of malformations and miscarriage was rare and difficult to assess because of the retrospective nature of the study. The commonest special features of the pregnancy were breech presentation (present in almost all cases of cranial abnormalities), foetal distress, dysgravidism and prematurity. The child with an external malformation is often born dead or dying and the organs most affected are the nervous and locomotor systems.
这项为期11年的回顾性研究显示,在总共64777例分娩中,有79例可见先天性畸形(患病率1.2%)。未发现病因特征。与文献数据相反,受累最多的产妇年龄在20至35岁之间,受影响最频繁的妊娠似乎是首次妊娠。由于研究的回顾性,既往畸形和流产史很少见且难以评估。妊娠最常见的特殊情况是臀位(几乎所有头颅异常病例均有)、胎儿窘迫、妊娠异常和早产。有外部畸形的患儿往往出生时已死亡或濒死,受影响最严重的器官是神经和运动系统。